{"id":6787,"date":"2016-12-22T17:06:41","date_gmt":"2016-12-23T01:06:41","guid":{"rendered":"https:\/\/wealththrunutrition.com\/?page_id=6787"},"modified":"2025-06-12T15:53:17","modified_gmt":"2025-06-12T15:53:17","slug":"lunasin-duke-als","status":"publish","type":"page","link":"https:\/\/wealththrunutrition.com\/uk\/lunasin-duke-als\/","title":{"rendered":"Lunasin Duke ALS Study"},"content":{"rendered":"<div id='av_section_1'  class='avia-section av-krpsqb-11909435c2b50032f585ef8a9b913632 main_color avia-section-default avia-no-shadow  avia-builder-el-0  avia-builder-el-no-sibling  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><main  class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-6787'><div class='entry-content-wrapper clearfix'>\n<section  class='av_textblock_section av-iq9z9f-348c6f000c56b26bfd844f888408f817 '  ><div class='avia_textblock' ><h2 style=\"text-align: center;\">Lunasin Duke ALS Study Information<\/h2>\n<p><strong>Lunasin<\/strong> is a peptide found naturally in soy and is a unique 43-amino soybean peptide.\u00a0It is now one of the most heavily researched and scientifically supported nutritional compounds available today.<\/p>\n<p>The lunasin Duke ALS study is ongoing, but not recruiting participants with the estimated completion date of September 2017. It is largely virtual, single-center, <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/study\/NCT02709330\" target=\"_blank\" rel=\"noopener\">open-label pilot trial<\/a> for patients with <strong>Amyotrophic Lateral Sclerosis (ALS)<\/strong> utilizing a historical control group. Participants will receive a Lunasin regimen (details under the heading\u00a0Arms in the above link) with 3 Reliv products \u2013 LunaRich X, Reliv Now, and ProVantage.<\/p>\n<p>There is another recent study that might explain why some with ALS are seeing results with the Reliv products containing the lunasin peptide. \u00a0\u201cUsing identical twins afflicted with familial ALS (amyotrophic lateral sclerosis), researchers from UCLA discovered that epigenetic changes to the expression of immune genes (the neurotoxic cytokines, IL-6 and TNFalpha), may activate ALS<strong>*<\/strong>. The presence of high amounts of these neurotoxic cytokines in the afflicted twin but not in the normal twin suggests that environmental factors may have caused the epigenetic increase in expression of these immune genes, leading to disease activation and progression.\u201d<\/p>\n<p>\u201cThis new finding provides a potential mode of action for the effect of the lunasin peptide on ALS patients, as part of the on-going Duke clinical trial. In a 2009 publication<strong>**<\/strong>, lunasin has been found to reduce the gene expression of the pro-inflammatory and neurotoxic cytokines, IL-1, IL-6 and TNFalpha in macrophage cells.\u201d Dr. Alfredo Galvez<br \/>\n<strong>*<\/strong>\u00a0<a href=\"\/uk\/wp-content\/uploads\/sites\/8\/2016\/12\/Epigenetic-changes-in-T-cell-and-monocyte-signatures.pdf\" target=\"_blank\" rel=\"noopener\">Epigenetic changes in T-cell and monocyte signatures and production of neurotoxic cytokines in ALS patients (PDF)<\/a><\/p>\n<p><strong>**<\/strong>\u00a0<a href=\"\/uk\/wp-content\/uploads\/sites\/8\/2016\/12\/Lunasin-and-lunasin-like-peptides-inhibit-inflammation.pdf\" target=\"_blank\" rel=\"noopener\">Lunasin and lunasin-like peptides inhibit inflammation through suppression of NF-kappaB pathway in the macrophage (PDF)<\/a><\/p>\n<\/div><\/section>\n<div  class='hr av-hmpieb-77cce3c801af47dea5cdcc3cc1929bb8 hr-default  avia-builder-el-2  el_after_av_textblock  el_before_av_textblock '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<section  class='av_textblock_section av-jjgd8acg-ec0e9d78f349f72d53e24c4e6cafeda6 '  ><div class='avia_textblock' ><p class=\"ai-optimize-6\">Over the last 2 years we have helped over 150 people dealing with this terrible disease. To find out more\u00a0<strong><a href=\"\/uk\/email-us\/\" target=\"_blank\" rel=\"noopener\">Email Us<\/a><\/strong>\u00a0or let&#8217;s connect via <strong><a href=\"https:\/\/fb.me\/msg\/WealthThruNutrition\" target=\"_blank\" rel=\"noopener noreferrer\">Facebook Messenger<\/a> <img decoding=\"async\" class=\"alignnone wp-image-5511 size-full\" src=\"\/uk\/wp-content\/uploads\/sites\/8\/2016\/04\/facebook-messenger-icon-20x20-1.png\" alt=\"Facebook Messenger - Wealth Thru Nutrition\" width=\"20\" height=\"20\" \/><\/strong>\u00a0or <strong><a href=\"https:\/\/api.whatsapp.com\/send?phone=16784881485\" target=\"_blank\" rel=\"noopener\"> WhatsApp<\/a><img decoding=\"async\" class=\"alignnone wp-image-8282 size-full\" src=\"\/uk\/wp-content\/uploads\/sites\/8\/2017\/08\/WhatsApp-20x20-1.jpg\" alt=\"Whats App - Wealth Thru Nutrition\" width=\"20\" height=\"20\" \/><\/strong>.<\/p>\n<p class=\"ai-optimize-7\">If we are online we can have a real-time discussion or offline leave your information and questions and we will get back to you as quickly as possible. All correspondence is always kept confidential. Praying for a cure!<\/p>\n<\/div><\/section>\n<div  class='hr av-hmpieb-77cce3c801af47dea5cdcc3cc1929bb8 hr-default  avia-builder-el-4  el_after_av_textblock  el_before_av_textblock '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<section  class='av_textblock_section av-f2m6jn-c5653df35678ae6f37bd93eb5742d001 '  ><div class='avia_textblock' ><p>The <strong>Lunasin Duke ALS<\/strong> protocol calls for patients to taper up to the target regimen as follows:<br \/>\nDay 1: 3 capsules of LunaRich X, \u00bc scoop of Reliv Now and \u00bc scoop of ProVantage (do this twice a day for 1 day).<br \/>\nDay 2: 4 capsules of LunaRich X, 1\/2 scoop of Reliv Now and 1\/2 scoop of ProVantage (do this twice a day for 2 days).<br \/>\nDay 4: 6 capsules of LunaRich X, 1 scoop of Reliv Now and 1 scoop of ProVantage (do this twice a day for 2 days).<br \/>\nDay 6: 6 capsules of LunaRich X, 1 1\/2 scoops of Reliv Now and 1 scoop of ProVantage (do this twice a day for study duration).<br \/>\nIt will be suggested that patients open the LunaRich X capsules and mix the contents of these as well as the other 2 ingredients in water to make a shake if they have a problem swallowing capsules. At the full dosage, it will require 3 cans of Reliv Now, 3 bottles of LunaRich X (120 ct), and 4 cans of ProVantage monthly.<\/p>\n<\/div><\/section>\n<div  class='avia-button-wrap av-2xkq83-b3bb6f7f00a3a1e22f8e9f9a2f3ac5e7-wrap avia-button-center  avia-builder-el-6  el_after_av_textblock  avia-builder-el-last '><a href=\"https:\/\/wealththrunutrition.com\/uk\/reliv-order\/\" class=\"avia-button av-2xkq83-b3bb6f7f00a3a1e22f8e9f9a2f3ac5e7 av-link-btn avia-icon_select-no avia-size-large avia-position-center avia-color-theme-color\" title=\"Reliv UK Order Now\" aria-label=\"Reliv UK Order Now\"><span class='avia_iconbox_title' >Order Now<\/span><\/a><\/div>\n<\/div><\/div><\/main><!-- close content main element --><\/div><\/div><div id='after_section_1'  class='main_color av_default_container_wrap container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-6787'><div class='entry-content-wrapper clearfix'>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-6787","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wealththrunutrition.com\/uk\/wp-json\/wp\/v2\/pages\/6787","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wealththrunutrition.com\/uk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wealththrunutrition.com\/uk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wealththrunutrition.com\/uk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wealththrunutrition.com\/uk\/wp-json\/wp\/v2\/comments?post=6787"}],"version-history":[{"count":0,"href":"https:\/\/wealththrunutrition.com\/uk\/wp-json\/wp\/v2\/pages\/6787\/revisions"}],"wp:attachment":[{"href":"https:\/\/wealththrunutrition.com\/uk\/wp-json\/wp\/v2\/media?parent=6787"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}